The most important K-beauty ingredients in 2025

At the end of 2024, we received a preview of upcoming trends for 2025 from Yeppo & Soonsoo CEO Elisa Ahonpää-Kim. Inspired by this interview, we have compiled an information-packed article about the most important skincare ingredients of the year! 😍 Why are these ingredients so popular? And which one is best suited for you? Let's take a closer look at these trending ingredients:

  • PDRN
  • Azelaic acid
  • Ectoine
  • PGA
  • Exosomes

PDRN: all in one product for well-aging skincare 🌟

PDRN (polydeoxyribonucleotide) is a DNA fragment extracted from the milt of salmon or other fish. This biotechnological ingredient has gained popularity in anti-aging skincare due to its ability to promote cell regeneration and tissue repair. Studies show that PDRN can stimulate fibroblasts—skin cells responsible for collagen production—helping the skin maintain elasticity and reducing wrinkles.

Additionally, PDRN is known for its anti-inflammatory properties and wound-healing capabilities, making it beneficial for sensitive and irritated skin. It is commonly used in aesthetic treatments such as microneedling and mesotherapy, but it is also effective in at-home skincare products like serums and creams.

What products does Yeppo have that contain PDRN?

Azelaic acid: for irritated and red skin 🥵

This naturally grain-derived ingredient acts as an antibacterial agent that helps reduce the growth of acne-causing bacteria and regulates excess sebum production. Thanks to its ability to break down keratin, it provides gentle exfoliation, supports cell turnover, and promotes a brighter, more radiant complexion. Azelaic acid is well known in the medical world for its ability to treat acne and rosacea.

In cosmetics, azelaic acid is not restricted under EU regulations, and most skincare products contain concentrations between 5–15%, which help soothe the skin while evening out tone and texture. In the U.S., azelaic acid is limited to a maximum of 10% in cosmetics, while concentrations of 15–20% are approved by the FDA for treating acne and rosacea.

Scientific studies have also shown that azelaic acid is effective in treating hyperpigmentation, as it inhibits the enzyme tyrosinase, thereby reducing melanin production. This makes it an excellent option for those struggling with uneven skin tone.

Azelaic acid is generally well tolerated and suitable for sensitive skin.However, for visible results with hyperpigmentation, it’s best combined with other brightening ingredients such as niacinamide or vitamin C. A concentration of at least 10%, preferably 15%, is recommended for optimal effect. And though well suited for sensitive skin, it's always advised to start slowly and do patch testing when trying out a new product or active ingredient.

Which azelaic acid products does Yeppo offer?

Ariul Expert Azelaic Acid 5% Ampoule – A great choice for calming the skin and targeting breakouts. This powerhouse formula also includes gold standard ingredients like vitamin C, peptides and retinaldehyde for maximum results 🌟

Ectoin - soothing care for extra sensitive skin: 

Ectoin is an amino acid derivative originally discovered in microorganisms living in extreme environments. It is known for its ability to protect skin cells from environmental stressors such as UV-induced damage, pollution, and dehydration. This makes ectoin an excellent ingredient for dry and sensitive skin, as it strengthens the skin barrier and reduces transepidermal water loss.

Studies have shown that ectoin can improve skin hydration while also reducing inflammation and irritation. It is a popular ingredient in soothing and moisturizing skincare products, such as serums and creams.

What products does Yeppo have, that contain ectoin? 

PGA: A hydration powerhouse 💦

Polyglutamic acid (PGA) is a hydrating ingredient composed of amino acids that binds water to the skin, similar to hyaluronic acid—some claim it even outperforms hyaluronic acid! What makes PGA special is its ability to form a protective film on the skin, preventing moisture loss and leaving the skin plumper and smoother. It is particularly beneficial for dry and dehydrated skin as it enhances elasticity and softness.

PGA works well in combination with other hydrating ingredients, such as hyaluronic acid, and may also help support the skin's natural moisturizing factors (NMF). Some studies suggest that PGA stimulates the production of NMF, making it a unique ingredient for maintaining skin hydration.

Fun fact: PGA was first discovered in natto, a traditional Japanese fermented food 🫘🥢

What products does Yeppo have, that contain PGA?

Exosomes - cell comunicating messangers: 

Exosome-based skincare is a new innovation that utilizes cellular communication systems in skincare. But what exactly are they?

Exosomes are tiny extracellular vesicles containing proteins, lipids, and RNA—essentially nano-sized messaging capsules that cells send to each other. In medicine, exosomes are particularly interesting because they can efficiently deliver therapeutic molecules to the body. In skincare, exosomes are being studied for their ability to promote skin regeneration, wound healing, and inflammation reduction. Their significance in skincare lies in their ability to facilitate cellular communication, which can stimulate skin renewal and collagen production.

Additionally, exosomes are gaining traction in hair care, as they can send signals to hair follicles and promote hair growth, making them an exciting ingredient for future skincare and haircare innovations 💫

How do I know if a product contains exosomes? Exosomes do not appear in ingredient lists under the name "exosome" but are instead a blend of various components such as water, lipids, and different active ingredients.

What products does Yeppo have that contain exosomes?

Summary

Skincare trends are constantly evolving, but one thing remains certain: skincare is becoming increasingly scientific and effective 🔬

PDRN, azelaic acid, ectoin, PGA, and exosomes are examples of how biotechnology and natural ingredients can create innovative and impactful skincare solutions 🌱 Each of these ingredients offers unique benefits, and the best choice depends on individual skin concerns and goals.

Challenge 1: Oily skin and enlarged pores

→ Try azelaic acid or exosomes, for example Medicube One Day Exosome Shot 2000 or SKIN1004 Centella Tea-Trica B5 Cream

Challenge 2: Sensitive and irritated skin that is prone to redness

Try azelaic acid for moderately sensitive skin. For highly sensitive skin, ectoin is also a great option to soothe and hydrate. A perfect product for this is  'hwarang' Bellflower Moisturizing Barrier Cream 

Challenge 3: Dry skin that struggles to absorb products

→ Try PGA, for example TIRTIR SOS Serum

Challenge 4: Signs of aging, wrinkles, and loss of firmness

→ Try PDRN or exosomes in cosmetics, for example VT Cosmetics PDRN Essence 100

Sources: 

https://www.sciencedirect.com/science/article/pii/S2096691122000723

https://www.mdpi.com/2079-9284/11/3/76

https://www.sciencedirect.com/science/article/pii/S2790676024000190

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